immune system Disorders
Mohammed Khaled Al-Falasi
What is a “Immune System Disorder” ?
A Immune system disorder is just a negative response from your body towards the substances that are normally present and alive in the body. This disorder is commonly know as a Autoimmunity and their disorders are “Autoimmunity Diseases” as a shortened version. The disorder can be cause be an overactive response towards the problem or non-activity. The overactivity of the response is called Autoimmunity as i’ve mentioned before, the lower-activity is called Immune Deficiency. Both of these disorders can reach to heights that can affect the body in ways that could lead to death over a long period of time. This subject is like a tree, it has many disorders and what causes them but the main two types are the ones i’ve mentioned them above. They’re are many types of immune system disorders, i am going to start explaining the simple ones first and then get into the details of the critical and the most effective ones after.
Allergies. Allergies are like moms, they overreact to anything that happens to their children. Allergies over-react to a non-threatening foreign particle or substances. When the body senses or detects allergens they release chemicals such as Histamine to treat it. (Yes, i did use an example for class :D) . Allergies have many symptoms, they may be as small as eye irritation or can be as affecting as Nausea and vomiting. Many other symptoms of allergies are Rashes, Eye Irritation, Nasal Congestion and Breathing problems. There are simple solution towards these Allergies are medications. There are many types medications but one of them is Antihistamine. Avoiding Allergen exposure is the safest and best way of preventing Allergies instead of going over the hassle to get those medications.
Allergies are especially unique in the medical field because they differ among patients. An allergy is a specific immunologic reaction to a normally harmless substance, one that does not bother most people. People with allergies are often sensitive to many substances. Common allergens that cause allergic reactions include seasonal, outdoor allergens like tree, grass, and weed pollen, and ...
Asthma is a condition in where the immune system becomes overactive in the lungs and specifically in the Bronchi. The causes or main cause of Asthma is not fully known yet, but it can be transferred or passed on by genetics. It is believed that Allergens trigger Asthma symptoms in very sensitive people. Asthma related triggers can be related to Exercise, Cold air, Pollen, Pet dander and even stress. These are just some of the examples. One of the biggest life-threatening symptom is an Asthma attack. An asthma attack is projected when the muscles and the lining of the passageways tighten and stop airflow from getting to the lunds. If this attack is very severe, it could lead to death. This attack also triggers another symptom and that is wheezing. Asthma can be treated in many ways, for example using Inhaled Corticosteroids and fast acting Bronchodilator. The best way to prevent getting Asthma attacks are avoiding Allergens or reactants that triggers Asthma.
rheumatoid arthritis is another disorder immune system disorder mainly cause by the overactivity of the system. The immune system produce antibodies that attach to the joint and cause joint-linings. Rheumatoid Arthritis (RA) shares symptoms with another condition that is not a disorder, (OA) Osteoarthritis. (RA) causes joint-linings, Inflammation of the joints, Pain, swelling and etc. (RA) has been reported to cause other kinds of indirect difficulties in the body to heart, eyes, and other parts. (RA) affect the bones in many ways causing the bones to erode over times which loses it shape and causing pain in walking and stiffness during walking also. Treating this disorder can be done by injecting yourself with oral medications that would level the overactivity in the body. nonsteroidal anti-inflammatory drug (NSAID).
Lupus is an autoimmune disease that attacks women between the ages of 15 and 40. It occurs less often in men than in women. The people affected by lupus vary depending on the country or region. In the US alone, the prevalence rate is highest among Asians of Hawaii, blacks of Caribbean origin, and Native Americans of the Sioux, Arapahoe, and Crow tribes. Lupus is a disease that affects the immune ...
This drug does not slow down the progression of (RA) but reduces the pain and inflammation. Biologics, The newest and most effective treatments for rheumatoid arthritis are biologics. Biologics are genetically engineered proteins. They are designed to inhibit specific components of the immune system that play a pivotal role in inflammation, a key component in rheumatoid arthritis. Biologics are usually used when other drugs have failed to stop the inflammation of rheumatoid arthritis. Biologics may slow or even stop RA progression.
Systemic Lupus Erythematosus (Lupus) is an autoimmune disorder that is caused by antibodies that attach around the body and it’s tissues. The antibodies usually attach in the Heart, Joints, Lungs, Blood Cells, Nerves and etc. Lupus can have many different combinations of symptoms causing Loss of Appetite, Fatigue, Fever(low-grade).
These symptoms that i’ve just mentioned are very small compared to the ones that are coming up. Skin manifestations are frequent in lupus and can sometimes lead to scarring. In discoid lupus, only the skin is typically involved. The skin rash in discoid lupus often is found on the face and scalp. It usually is red and may have raised borders. Discoid lupus rashes are usually painless and do not itch, but scarring can cause permanent hair loss (alopecia).
Over time, 5%-10% of those with discoid lupus may develop SLE.
Severe Combined Immune Dificinency (SCID) is a condition that is very rare and it is inherited that results in a weak immune system, this disorder is known for not fighting mild infections due to the effect of the T-cells. (SCID) is a immune deficiency case, Symptoms of the disease are frequently first noticed very early in life. Infants with (SCID) often suffer from recurrent, severe respiratory infections. These infections are usually serious and may even be life-threatening. Still, it may require several hospitalizations before (SCID) is diagnosed. There are several forms of (SCID).
The most common type is linked to a problem in a gene on the X chromosome, affecting only males. Women may carry the condition, but they also inherit a normal X chromosome. Men, on the other hand, have only one X chromosome. Many other symptoms have been related to this disorder but may not be present all the time, Chronic Diarrhea, Poor Growth by, Rashes that look like eczema. (SCID) can be cured in one way and that is through a bone marrow transplant giving the patient a new immune system. Gene therapy has also been trialed as a treatment, it has been successful many times but with complications.
INTRODUCTION In order to provide a detailed analysis of recent pharmacological developments involving the human immune system, it is firstly necessary to introduce the innate and adaptive immune responses . Immunosuppressants and immunomodulators will be differentiated between and a selection of new and often experimental drugs belonging to each category will be provided. Specific drugs will be ...
Common Variable Immune Dificiency (CVID) Common Variable Immune Deficiency (CVID) is a frequently diagnosed immunodeficiency, especially in adults, characterized by low levels of serum immunoglobulins and antibodies, which causes an increased susceptibility to infection. While CVID is thought to be due to genetic defects, the exact cause of the disorder is unknown in the large majority of cases. the immune system produces too few antibodies to effectively fight infections. Children with CVID typically have frequent infections of the ears, lungs, nose, eyes, and other organs. Treatment includes replacing the missing antibodies with regular injections of antibodies, called immunoglobulins.