I am doing my report on hemophilia. Hemophilia is a terrible and nasty genetic disease. It affects ones ability to form a blood clot to stop bleeding. Hemophilia is a genetic disease. This means that the disease is passed down through the generations by means of our genetic codes, or genes.
Humans are made up of 46 chromosomes, which have the battle plans for various functions, actions, and makeup of the body. These are 23 chromosome pairs. Chromosomes also determine whether or not we will be male or female. These two chromosomes labeled “x” and “y.” A male will have one “x” and one “y” and females will have two “x’s” Usually males are the only ones who get hemophilia.
Hemophilia is found on the “x” chromosome at the very bottom and when it occurs people suffer from the inability to form firm clots. Which, means in short, that they bleed, and keep bleeding. One of the most scary and interesting things about genetic diseases is the fact that they are passed down through generations of people. They often don’t show up for a couple of generations and then come back in full force.
This puzzled many scientists long ago, but then tools were developed that can map and show how these diseases are passed down. To understand what is to come, certain things must be clear. Meiosis is THE crucial part of passing down genetic diseases. Meiosis is a process by, which cells divides and multiply down until the male’s cell becomes sperm cells, and the female’s cell becomes an egg. Also, in the diagrams below, “xy” means male, and “xx” means female, and if there is a “h” by it, that chromosome carries the disease. Only a “x” chromosome will carry hemophilia.
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The first of the tools scientists use to track diseases is called a pedigree. The first of the tools scientists use to track diseases is called a pedigree. A pedigree shows all the males and females of a family and then shows which person had what. Half the shape being filled in marks carriers, and people who have and show the disease are completely filled in. People with no signs of the disease what so ever, are not filled in at all.
Look at the pedigree below and watch how the disease moves through the family members shows all the males and females of a family and then shows which person had what. Half the shape being filled in marks carriers, and people who have and show the disease are completely filled in. People with no signs of the disease what so ever, are not filled in at all. Look at the pedigree below and watch how the disease moves through the family members. Here is a picture of a pedigree. Another tool that scientists use is called a Punnett Square.
This shows the possible outcomes of childbirth between a male and female. If you look to the below, you see an example of a Punnett Square. The male is on the top of the square, and has hemophilia because his one “x” chromosome has the disease. (Represented by the small “h”) The female is completely clean from the disease. All of the people represented inside the box are the possible offspring.
In this case, if the couple have a daughter, it will be a carrier no matter what. (Represented by one of the “x’s having the disease) If the couple has a son, he will be completely ok no matter what. Well there is my report on hemophilia. I hope you learned as much about hemophilia as I did. Thank you for your time.
