Inflammation #
Please compare and contrast acute vs chronic inflammation. A thorough answer should include subtypes of acute inflammation; relevant cell types (and their functions) and biochemical mediators attracted. Please also discuss in detail at least one relevant disease example.
Please compare and contrast acute vs chronic inflammation. Your
answer should provide a detailed discussion of what elements (e.g.,
cells, proteins etc) are required for each as well as any interplay (if any)
between the two systems.
Compare and contrast acute versus chronic inflammation. A complete
answer would include possible causes, the sequence of cellular and/or
molecular events, relevant cell types affected and specific (disease)
examples, as appropriate.
1. Compare and contrast acute versus chronic inflammation. A complete answer would include possible causes, the sequence of cellular and/or molecular events, relevant cell types affected and specific (disease) examples, as appropriate (35 marks).
Neoplasia
Please discuss the key genetic events needed to convert a normal human cell into a neoplastic cell. Your answer should also include a thorough description of the key classes of genes affected in this transformation with discussion of their function(s) when “normal” or “mutated”. Credit awarded for essays which use specific gene examples as appropriate.
Compare contrast essay
Novelist Paul Sheldon has plans to make the difficult transition from writing historical romances featuring heroine Misery Chastain to publishing literary fiction. Annie Wilkes, Sheldon’s number one fan, rescues the author from the scene of a car accident. The former nurse takes care of him in her remote house, but becomes irate when she discovers that the author has killed Misery off in his ...
Please discuss carcinogenesis with respect to (at least) three classes
of agents which initiate a tumour, with specific examples and
mechanisms of action (e.g., how they initiate a tumour) as appropriate.
Please also include in your answer a discussion of the ways in which
carcinogen-dependent tumourigenesis can be blocked.
2. Discuss the fundamental changes in cell physiology which dictate a malignant phenotype. Specific examples should be utilised when appropriate (35 marks).
Cell cycle
Please discuss entry into, movement through and exit from the cell cycle. A complete answer should include the sequence of molecular events which induces cells to enter the cell cycle from quiescence; specific proteins needed to transition into each cell cycle phase as well as proteins which act to arrest progress at different points in the cell cycle. Please provide specific temporal examples.
Describe the mechanisms by which healing and scar formation
Review in detail the major processes that occur in tissues during wound healing
