Part I: Due Friday, January 25th 2013. Type or Hand Write in Ink.
Research Huntington’s disease and answer these questions. (10 pts) a.
Do this first!
What is Huntington’s Disease
b. How is it caused on a genetic level? Be specific about the chromosome #, genetic mutation, dominant or recessive, and chance of inheriting the disorder. c. What are symptoms?
d. Is there a cure? What are treatments?
**Include cites from at least 2 reliable sources.
Part II: Due ______________________. Reading Guide Questions and Essay *Be sure to include page numbers and quotes from the novel, when appropriate, to ensure a complete answer and full credit.
1. What is the connection between what Wyatt Transgenics Company does and the reference to the comic “The Swamp Thing”? (2 pts) The connection between Wyatt Transgenics and the comic is that in the company they alter organism’s genes and that’s what had happened to the Swamp Thing (pg 64) 2. What does the term “transgenic” mean? (2 pts)
Transgenic is when an organism is altered by having a gene from another species transferred into the original organism. (pg 64) 3. How do the scientists make the animals develop the desired proteins? How do scientists access the proteins? Provide the 3 exact details. (4 pts) The scientist make the proteins by giving the rabbits the transgenic genes, then in the rabbit the genes make the rabbits produce the proteins in their milk, and then they milk the rabbits and purify the proteins out of the milk. (pg 67) 4. How can the proteins from the animals’ milk be used? (2 pts) The proteins can be used for treatments for arthritis and cancer and several other conditions that affect the immune system. (pg 67) 5. When was testing for Huntington’s disease first made legal? Explain how Eli’s parents were able to get him tested. (2 pts) Huntington’s disease was first made legal in 1968. Eli’s parents were able to get him tested so young because they said it was Eli’s father getting tested because he was over 18. 6. Based on the novel, what is a chimera? (2 pts)
Huntington's Background Huntington's disease is inherited as an autosomal dominant disease that gives rise to progressive, elective (localized) neural cell death associated with choreic movements (uncontrollable movements of the arms, legs, and face) and dementia. It is one of the more common inherited brain disorders. About 25,000 Americans have it and another 60,000 or so will carry the ...
A chimera is a being that is created by a recombination of DNA from different sources. (pg 189) 7. How does the term chimera relate to Eli and Kayla? (2 pts) The term chimera relates to them because both of them were made because Eli’s mom had Huntington’s so they “made” both of the kids. 8. What is the genetic marker for Huntington’s disease? (2 pts) The genetic marker for Huntington’s is huntingtin.
9. Should the acts of Dr. Wyatt be considered legal? Why or why not? (4 pts) Yes, because it was for the sake of not getting Huntington’s. It should be legal because that way Eli would not have had to struggle through the disease. 10. What are the names of the nucleotides notated as C-A-G? (2 pts) The names are cytosine-adenine-guanine.
11. Do you agree with the disabled man mentioned in the epilogue? Why or why not? (4 pts) Yes, because he says there is nothing wrong with having down’s syndrome so why would people want to stop this disease because they don’t harm anyone. 12. If you were in Eli’s position, would you choose to be tested for Huntington’s? Explain why or why not with points mentioned in the book. (6 pts) I would say yes. Even though I would be afraid to know the truth its better to know ahead of time instead of it just starting to happen one day. Also because he would want to protect the children he would have. 13. Describe how Dr. Wyatt made sure that Ava’s baby would be negative for Huntington’s disease. There are 2 specific steps. (2 pts) He made sure by taking her eggs and finding which ones would not have the gene and then inserting the sperm that would be also not have the gene.
Huntington disease is a form of an inherited neurodegenerative disorder. The disease appears following a mutation of one of a person’s two copies of a Huntingtin gene which is autosomal. This gene is normally found in all individuals and its function is to code for a protein which is known as huntingtin. Following the mutation of this gene, a different type of protein is formed and this protein ...